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法舒地尔联合尼莫地平对老年性痴呆的疗效

严斌 孙芳 段立晖 彭巧玲 赵文新 周国庆

实用临床医药杂志2011,Vol.15Issue(13):92-93,98,3.
实用临床医药杂志2011,Vol.15Issue(13):92-93,98,3.

法舒地尔联合尼莫地平对老年性痴呆的疗效

Curative effect of Fasudil injection combined with Nimodipine on Alzheimer disease of elderly patients

严斌 1孙芳 1段立晖 1彭巧玲 1赵文新 1周国庆1

作者信息

  • 1. 南京军区南京总医院,干部神经内科,江苏,南京,210002
  • 折叠

摘要

Abstract

Objective To investigate the curative effect of Fasudil injection combined with Nimodipine on the Alzheimer disease of elderly patients. Methods 106 elderly patients with the Alzheimer disease randomly selected and divided into 2 groups. 53 cases in control group were treated with Nimodipine, while 53 cases in treatment group were treated with Fasudil injection combined with Nimodipine. The score was detected before and after treatments according to the MMSE, VET and ADL. Results The MMSE and VFT score increased obviously and the ADL score decreased in treatment group after treatments(P<0.05). The total efficiency in treatment group was 90.57% versus 66.04% in control group(P<0.05).Conclusion Compared with Nimodipine, Fasudil injection combined with Nimodipine has a better effect on the Alzheimer disease of elderly patients.

关键词

尼莫地平/法舒地尔/阿尔茨海默病

Key words

Nimodipine/ Fasudil injection/ Alzheimer disease

分类

医药卫生

引用本文复制引用

严斌,孙芳,段立晖,彭巧玲,赵文新,周国庆..法舒地尔联合尼莫地平对老年性痴呆的疗效[J].实用临床医药杂志,2011,15(13):92-93,98,3.

实用临床医药杂志

OACSTPCD

1672-2353

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