同位素稀释高效液相色谱-串联质谱法测定水产品中甲苯咪唑及其代谢物的残留量OA北大核心CSCDCSTPCD
Simultaneous Determination of Mebendazole and Its Metabolites Residues in Fishery Products by High Performance Liquid Chromatography Tandem Mass Spectrometry with Isotope Dilution
建立了同时分析水产品中甲苯咪唑及其代谢物羟基甲苯咪唑和氮基甲苯咪唑的同位素稀释高效液相色谱串联质谱法.向样品中添加磷酸二氢钠溶液后用乙酸乙酯提取,提取液用氮气吹干后经2 mL甲醇-0.1%甲酸溶液(体积比1:1)溶解,正己烷去脂.以Hypersil GOLD为色谱分离柱,甲醇-0.1%甲酸溶液为流动相,流速为0.2 mL/min,用配有加热电喷雾离子源的三重四极杆质谱进行选择反应离子监测.3种化合物在0.5～100μg/L范围内呈良好线性,相关系…查看全部>>
A rapid method of liquid chromatography tandem mass spectrometric( HPLC -ESI MS/MS) with isotope dilution was developed for the simultaneous determination of residual mebendazole (MBZ) and its metabolites e.g. hydroxy-mebendazole ( MBZ - OH ) and amino-menbendazole ( MBZ - NH2 ) in fishery products. The sample, after adding disodium phosphate, was extracted with ethyl acetate. The extract was evaporated to dryness under nitrogen, and redissolved in 2 mL meth…查看全部>>
刘永涛;艾晓辉;杨红
中国水产科学研究院,长江水产研究所,农业部淡水鱼类种质监督检验测试中心,湖北武汉,430223中国水产科学研究院,淡水渔业研究中心,江苏无锡,214081中国水产科学研究院,长江水产研究所,农业部淡水鱼类种质监督检验测试中心,湖北武汉,430223
化学化工
同位素稀释甲苯咪唑羟基甲苯咪唑氨基甲苯咪唑代谢物高效液相色谱-串联质谱法水产品
isotope dilution menbendazole hydroxy-mebendazole amino-menbendazole metab-olites HPLC - MS/MS fishery products
《分析测试学报》 2011 (6)
640-645,6
农业行业标准制定项目资助中央级公益性科研院所基本科研业务费专项资金资助项目(2011JBFA19)
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