临床肝胆病杂志2011,Vol.27Issue(7):735-737,748,4.
血清内脏脂肪素、脂联素与非酒精性脂肪性肝病临床病理的关系
Relationship between serum visfatin and serum adiponectin level and the pathology of nonalcoholic fatty liver disease
朱超慧 1陈东风 2艾正琳 2杨丽 2闵敏2
作者信息
- 1. 解放军309医院消化科,北京,100091
- 2. 第三军医大学大坪医院消化科,重庆400042
- 折叠
摘要
Abstract
Objective To explore the relationship between serum visfatin and adiponectin levels and the pathology of NAFLD.Methods 54 patients were divided into 3 groups according to the pathology, including control group, simple steatosis group, and nonalcoholic steatohepatitis group.Serum visfatin and adiponectin levels were measured by enzymelinked immunosorbent assay.Results Among the 54 patients, control group includes 23 cases; simple steatosis group comprises of 11 cases; while nonalcoholic steatohepatitis group contains 20 cases.The level of serum visfatin of NASH group is lower than that of control group and simple steatosis group.Moreover, the change of serum adiponectin of NASH is as same as serum visfatin.Conclusion In NAFLD patients, the more severe the changes of steatosis and inflammation of the histopathology in liver, the lower levels of visfatin and adiponectin in plasma concentrations were showed.关键词
脂肪肝/内脏脂肪素,脂联素Key words
fatty liver/ visfatin, adiponectin分类
医药卫生引用本文复制引用
朱超慧,陈东风,艾正琳,杨丽,闵敏..血清内脏脂肪素、脂联素与非酒精性脂肪性肝病临床病理的关系[J].临床肝胆病杂志,2011,27(7):735-737,748,4.