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持续气道正压通气治疗对OSAHS患者胰岛素抵抗的影响

乔珊 孙艳荪 李雪梅

昆明医学院学报2011,Vol.32Issue(6):136-139,4.
昆明医学院学报2011,Vol.32Issue(6):136-139,4.

持续气道正压通气治疗对OSAHS患者胰岛素抵抗的影响

Efects of Continuous Positive Airway Pressure Treatment on Insulin Resistance in Patients with Obstructive Sleep Apnea Hypopnea Syndrome

乔珊 1孙艳荪 1李雪梅1

作者信息

  • 1. 北京大学深圳医院,广东深圳518000
  • 折叠

摘要

Abstract

Objective To investigate the effects of continuous positive airway pressure (CPAP) treatment on insulin resistance in patients with obstructive sleep apnea hypopnea syndrome (OSAHS).Methods Sixty patients with OSAHS were recruited.Their apnea hypopnea index (AHI) was 38.9 ± 16.0, and BMI maintained at (27.1 ± 2.5) kg/m2.The homeostasis model assessment (HOMA) index was used to reflect IR and before and after 3 months' GPAP treatment.Results The HOMA index was significantly lower following 3 months' GPAP treatment than before treatment (2.04 ± 1.78 vs 3.53 ± 2.76, P < 0.001 ).Gonclusion GPAP treatment can significantly improve IR in OSAHS patients, which suggests that OSAHS is an independent risk factor of IR.

关键词

阻塞性睡眠呼吸暂停低通气综合征/持续气道正压通气/胰岛素抵抗

Key words

Obstructive sleep apnea hypopnea syndrome/ Continuous positive airway pressure/ Insulin resistance

分类

医药卫生

引用本文复制引用

乔珊,孙艳荪,李雪梅..持续气道正压通气治疗对OSAHS患者胰岛素抵抗的影响[J].昆明医学院学报,2011,32(6):136-139,4.

昆明医学院学报

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