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原发性胆汁性肝硬化与弥漫结缔组织病的肝损伤

张奉春

临床肝胆病杂志2011,Vol.27Issue(6):588-590,3.
临床肝胆病杂志2011,Vol.27Issue(6):588-590,3.

原发性胆汁性肝硬化与弥漫结缔组织病的肝损伤

Primary biliary cirrhosis and liver disease secondary to diffuse connective tissue diseases

张奉春1

作者信息

  • 1. 中国医学科学院北京协和医院风湿免疫科,北京100032
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摘要

Abstract

Autoimmune liver disease comprises of a group of liver-targeting autoimmune diseases, whereas diffuse connective tissue disease (DCTD) is a group of non-organ-specific autoimmune diseases. Increasing evidences have suggested that these two groups of disorders are closely related, not only by their clinical manifestations but also their basic immunological mechanisms. This paper focuses on correlation between DCTD and primary biliary cirrhosis (PBC), including their overlapping rate, clinical symptoms, autoantibody profile as well as their pathological and immunological differences, so as to update our knowledge of PBC and liver disease secondary to DCTD, and promote more profound investigation to improve our diagnosis and treatment of these disorders.

关键词

肝硬化,胆汁性/结缔组织疾病/肝疾病/自身免疫疾病

Key words

liver cirrhosis, biliary/ connective tissue diseases/ liver diseases/ autoimmune diseases

分类

医药卫生

引用本文复制引用

张奉春..原发性胆汁性肝硬化与弥漫结缔组织病的肝损伤[J].临床肝胆病杂志,2011,27(6):588-590,3.

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