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儿童及青少年非酒精性脂肪性肝病的确诊及危险因素评估

张一宁 杜红伟 刘彦军 王朝霞

临床肝胆病杂志2011,Vol.27Issue(7):690-693,4.
临床肝胆病杂志2011,Vol.27Issue(7):690-693,4.

儿童及青少年非酒精性脂肪性肝病的确诊及危险因素评估

The diagnosis and risk factors for evaluation of nonalcoholic fatty liver disease in children and adolescents

张一宁 1杜红伟 1刘彦军 2王朝霞1

作者信息

  • 1. 吉林大学第一医院小儿内分泌遗传代谢科,长春,130021
  • 2. 美国加州大学查尔斯医学院内分泌实验室,美国南加州
  • 折叠

摘要

Abstract

Non-alcoholic fatty liver disease (NAFLD) in children and adolescents is considered to be a syndrome that is histologically characterized by hepatic steatosis and the accumulation of large droplets of triglycerides within hepatocytes in the absence of chronic alcohol consumption. NAFLD is a representation of the metabolic syndrome and insulin resistance in the liver. In children, NAFLD has been consistently associated with obesity, gender, insulin resistance and puberty. Thus, the diagnosis and risk factors for evaluation of NAFLD in children and adolescents need strong consideration of multiple risk factors such as gender and pubertal development etc different from adults.

关键词

脂肪肝/危险因素/肥胖症

Key words

fatty liver/ risk factors/ obesity

分类

医药卫生

引用本文复制引用

张一宁,杜红伟,刘彦军,王朝霞..儿童及青少年非酒精性脂肪性肝病的确诊及危险因素评估[J].临床肝胆病杂志,2011,27(7):690-693,4.

临床肝胆病杂志

OACSTPCD

1001-5256

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