四川医学2011，Vol.32Issue(7)：1140-1143,4.
一起风疹疫情的流行病学调查
With epidemiological epidemics of the measles
刘伟 1何吉兰 2李福民3
作者信息
- 1. 四川大学华西医院皮肤科,四川成都610041
- 2. 四川省疾病预防控制中心,四川成都610041
- 3. 四川省人民医院,四川成都610072
- 折叠
摘要
Abstract
Objective The purpose of the study was to investigate into a rubella outbreak among the Sichuan Province,China. And analyses the cause of divergence affectability in different ethnology. Methods In this study, we analysed a rubella outbreak occurred among the Vietnamese in South west Jiaotong University(SWJTU) Sichuan Province, 2006, and investigate the similar outbreaks of disease before it. Focusing on understanding the cause of why outbreaks limited in Vietnamese. We isolate RV from specimens in Vero-Slam cell, and detect the genotype of isolated RV by RT-PCR and sequence analysis. Results the total morbidity during Vietnamese in SWJTU is 10.8 per cent, witch is mach higher than the morbidity of RV outbreak during 2006 0.314 per cent.The living and studying environment of both Chinese and Vietnamese students is same. It was possible to Chinese students in SWJTU infected with same RV. We definite the infected chance of 21 Chinese students by field investigation. Genotypes of the 2 isolated wild RV are both 2B, witch is the first time in Sichuan Province. It showed a low degree of similarity with nucleotide variation between the 2 isolated wild RV and the advantage RV strains in China at present, and an highest degree of similarity between the 2 isolated wild RV and the wild RV strain in Indian(TAN-IND-00) with genotype of 2B. Conclusion The rubella outbreak occurred in SWJTU 2006 was caused by the RV with genotype of 2B, which was most likely inputted from Viet nam. The RV outbreak limited in Vietnamese was referable to ethnology besides other reasons.关键词
风疹/疾病暴发/流行病学调查/基因型Key words
rubella/ an outbreak/ epidemiological survey/ genotype分类
医药卫生引用本文复制引用
刘伟,何吉兰,李福民..一起风疹疫情的流行病学调查[J].四川医学,2011,32(7):1140-1143,4.
