广东药学院学报2011，Vol.27Issue(3)：260-263,4.DOI:10.3969/j.issn.1006-8783.2011.03.012
微波辐射对苦参碱提取的影响及其动力学和热力学机理研究
Effect of microwave irradiation on extraction of matrine from Sophora fiavescens Ait. and investigation of its kinetic and thermodynamic mechanism
摘要
Abstract
Objective To investigate the effects of factors such as microwave power and irradiation time etc on extraction of matrine from Sophora fiavescens Ait., and the mechanism of its process. Methods After microwave irradiation,the material of Sophorafiavescens Alt. was refiuxed in methanol to extract matrine,which was named as microwave-irradiation solvent reflux extraction (MISRE). The comparative study of extraction of matrine was performed with MISRE and solvent reflux extraction (SRE) methods. The influence of microwave irradiation on the extraction process was discussed from its kinetic and thermodynamic mechanism. Results The extraction process of matrine can be intensified through pretreatment of the medicinal material by microwave irradiation, in which its apparent rate constant increased, and activation energy was reduced significantly. Greater AH0 and AS0,less AGo of matrine than SRE were observed. Conclusion Compared with conventional SRE, this pretreatment can improve its extraction rate and efficiency. MISRE is simple,effective and easy to operate.关键词
微波辐射/提取/苦参/苦参碱/机理Key words
rhicrowave irradiation/ extraction/ Sophora flavescens Ait./ matrine/ mechanisms分类
医药卫生引用本文复制引用
佘旭辉,陈浩浩,黄晓文,井楠楠,陈俊彪,范华均..微波辐射对苦参碱提取的影响及其动力学和热力学机理研究[J].广东药学院学报,2011,27(3):260-263,4.基金项目
广州市科技支撑计划项目(2008Z1-E301) （2008Z1-E301）
广东药学院师资队伍建设基金(52104109) （52104109）
