广东药学院学报2011，Vol.27Issue(3)：327-331,5.DOI:10.3969/j.issn.1006-8783.2011.03.030
细胞色素P450与中草药代谢关系的研究进展
Review on interactions between cytochrome P450 and metabolism of medicinal herbs
摘要
Abstract
Cytochrome P450 (CYP450) is one of the microsomal mixed function oxidases, and plays an important role in the metabolism of exogenous and endogenous materials. Drug-relevant CYP, the relationship of CYP and drug interaction,and effects of Chinese herbal medicines on CYP are reviewed. It will help to explain and predict the clinical drug interactions and the adverse drug reactions. Suitable methods can thus be selected to evaluate the actions of CYP, and to offer a scientific basis for clinical individual therapy.关键词
细胞色素P450/中草药/药物相互作用/药物代谢Key words
cytochrome P450/ Chinese herbal medicine/ drug interaction/ drug metabolism分类
生物科学引用本文复制引用
张小梅,冯毅凡,陈耕夫,石忠峰..细胞色素P450与中草药代谢关系的研究进展[J].广东药学院学报,2011,27(3):327-331,5.基金项目
国家自然科学基金(30801543) （30801543）
