重庆医学2011，Vol.40Issue(24)：2404-2406,2409,4.DOI:10.3969/j.issn.1671-8348.2011.24.005
208例手术切除的ⅢA-N2期非小细胞肺癌患者的生存分析
Survival and prognostic factors in completely resected ⅢA-N2 non-small cell lung cancer: 208 cases study
摘要
Abstract
Objective To investigate clinical prognostic factors of completely resected stage ⅢA N2 non small cell lung cancer (NSCLC). Methods Proceeding survival analysis of 208 pathological Stage ⅢA N2 NSCLC patients with completely resection in Cancer center of Sun Yatsen University from Jan 2000 to Dec 2004. Prognostic factors were estimated with Kaplan Meier and logrank analysis. Using Cox regression model to evaluate the influence of factors on the survival. Results Median survival time for this patient population was 769 days and 1,2,3,4,5 year overall survival were 80.1 ％, 55.2 ％,36.6 ％, 29.2 ％ and 20.9 ％. Univariate analysis identified 5 significant prognostic clinical factors including age,preoperative serum CEA and LDH elevation,postoperative chemotherapy, numbers of postoperative chemotherapy cycles. Postoperative radiotherapy and anemia were marginally significant. In multivariate analysis,4 independent prognostic factors entered the model: preoperative serum CEA and LDH elevation,postoperative chemotherapy and radiotherapy. Conclusion Preoperative serum CEA elevation,preoperative serum LDH elevation,postoperative chemotherapy and radiotherapy have the prognostic significance in postoperative stage ⅢA N2 NSCLC.关键词
癌,非小细胞肺/预后/抗肿瘤联合化疗方案Key words
carcinoma/non small cell lung/prognosis/antineoplastic combined chemotherapy protocols引用本文复制引用
林勇斌,戎铁华,梁颖,李明毅,林鹏,傅剑华,张兰军,龙浩,王思愚,曾灿光..208例手术切除的ⅢA-N2期非小细胞肺癌患者的生存分析[J].重庆医学,2011,40(24):2404-2406,2409,4.基金项目
广东省卫生厅基金资助(B2009089). （B2009089）
