重庆医学2011，Vol.40Issue(24)：2413-2414,2.DOI:10.3969/j.issn.1671-8348.2011.24.008
易瑞沙治疗42例化疗失败的晚期肺腺癌的临床观察
Effects of iressa on 42 cases of chemotherapy failed advanced lung adenocarcinoma
马惠文 1余慧青 1邵江河1
作者信息
- 1. 重庆市肿瘤研究所、肿瘤医院肿瘤内科,400030
- 折叠
摘要
Abstract
Objective To evaluate the antitumor efficacy and adverse effects of single drug iressa in treatment of advanced lung adenocarcinoma patients who underwent failure during in previous chemotherapy. Methods 42 patients with chemotherapy failed advanced lung adenocarcinoma were given iressa 250 mg once a day until disease progression or occurrence of intolerable toxic reaction. Results Among 42 cases,2cases(4.76％)were in CR,25 cases (59.52％)were in PR,10 cases (23.81％)were in SD,and 5 cases (11.90％) were in PD;the total effective rate was 64.26％,disease control rate was 88.06％. Median overall survival time was l0.6 months. One year survival rate was 45.0％. The most common adverse effects were skin reactions and diarrhea. Conclusion It is effective and safe for iressa to treat advanced lung adenocarcinoma patients who underwent failure during in previous chemotherapy.关键词
治疗/易瑞沙/肺腺癌Key words
therapy/ iressa/ lung adenocarcinoma引用本文复制引用
马惠文,余慧青,邵江河..易瑞沙治疗42例化疗失败的晚期肺腺癌的临床观察[J].重庆医学,2011,40(24):2413-2414,2.
