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AFP、CEA和CA199联合检测在原发性肝癌诊断中的应用

董菊子 邓芝云 张峰 彭俊华

西北国防医学杂志2011,Vol.32Issue(4):276-277,2.
西北国防医学杂志2011,Vol.32Issue(4):276-277,2.

AFP、CEA和CA199联合检测在原发性肝癌诊断中的应用

Diagnostic value of combined detection of AFP, CEA and CA199 in primary fiver cancers

董菊子 1邓芝云 1张峰 1彭俊华1

作者信息

  • 1. 兰州军区兰州总医院检验科,甘肃,兰州,730050
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摘要

Abstract

Objective:To study the clinical value of combined detection of the serum levels of AFP, CEA and CA199 in primary liver cancers.Methods:Collecting the serum samples from 110 primary hepatic cancer patients and 152 benign liver disease patients (hepatic cirrhosis and chronic hepatitis), the serum levels of AFP, CEA and CA199 were measured by chemiluminescence.Results: The levels of AFP, CEA and CA199 were (60.6 ±80.5) μg/L, (22.2 ± 13.9) μg/L and (47.2 ± 28.3 ) U/L in primary liver cancer patients respectively, it was significantly higher than that in benign liver disease patients.The serum positive ratio of AFP, CEA and CA199 in primary liver cancer patients were 74.6%, 49.1% and 45.6%, respectively, it was significantly higher than that in benign liver disease patients too.The sensitivity of combined detection of three kinds of tumor markers was 92.7%.Conclusion: The combined detection of AFP, CEA and CA199 can arise the diagnosis sensitivity of primary hepatic cancer, it has some value in screening primary hepatic cancers.

关键词

原发性肝癌/AFP/CEA/CA199

Key words

Primary hepatic cancer/ AFP/ CEA/ CA199

分类

医药卫生

引用本文复制引用

董菊子,邓芝云,张峰,彭俊华..AFP、CEA和CA199联合检测在原发性肝癌诊断中的应用[J].西北国防医学杂志,2011,32(4):276-277,2.

西北国防医学杂志

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