河北医学2011，Vol.17Issue(9)：1238-1240,3.DOI:10.3969/j.issn.1006-6233.2011.09.044
74株流感嗜血杆菌的耐药性分析
Analysis the Antibiotic Resistance of 74 Strains Haemophitus Influenzae
江秀爱 1赵自云 1朱婕1
作者信息
- 1. 山东省青岛市中心医院检验科,山东,青岛,266042
- 折叠
摘要
Abstract
Objective: To investigate the distribution and the antibiotic resistance of clinical isolates of haemophilus influenzae for guiding antibiotic practice. Method: 74 clinical isolates of haemophilus influenzae were identificated by MicSCAN4 semi-automatic analyzer and HNID identification plate. Antimierobial susceptibility was tested by Kirby-Bauer method, and Beta-laetamases were detected by nitrucefin filter paper method. Result: 134 clinical isolates of haemophilus infiuenzae were mainly collected from sputum,throat swabs and other respiratory tract specimens, accounting for 97.2％. Resistance rate of haemophilus infiuenzae to TMP/SMZ was the highest,as high as 48.6％ ,and that to ampicillin was 42.9％ ,while up to 90％ of haemophilus influenzae were susceptible to cefotaxime, cefuroxime, chloramphenicol, azithromycin,amoxicillin/clavulanie acid,The prevalence of beta-lactamase of all strains was 41.0％. Conclusion: The haemophilus influenzae isolates were mainly isolated from respiratory tract specimens. It shows sensitive to the majority of antibiotics, but more than 48.6％ strains are non-sensitive to trimethoprim-sulfamethoxazole.Trimethoprim-suffamethoxazole is unsuitable to treat infections caused by haemophilus influenzae for experiential therapy.关键词
流感嗜血杆菌/耐药性/药敏试验Key words
Haemophitus influenzae/ Drug resistance/ Antimicrobial susceptibility引用本文复制引用
江秀爱,赵自云,朱婕..74株流感嗜血杆菌的耐药性分析[J].河北医学,2011,17(9):1238-1240,3.
