临床肝胆病杂志2011，Vol.27Issue(8)：833-836,4.
数字图像测定失代偿期乙型肝炎肝硬化肝组织纤维面积比例
Determination of the collagen proportionate area of hepatic tissue in HBV - related decompensated cirrhosis using digital image analysis
摘要
Abstract
Objectives digital image analysis was used to quantitatively determine the collagen proportionate area (CPA) of resected hepatic tissue after liver transplantation due to chronic hepatitis B - induced decompensated cirrhosis. Methods A total of 53 hepatic tissue samples resected from liver transplant patients with chronic hepatitis B - induced decompensated cirrhosis were collected. Masson stains of the hepatic tissue were performed. Digital image analysis was used to quantitatively determine the collagen proportionate area of the hepatic tis sue. Results The mean collagen proportionate area at the decompensated cirrhosis stage was (35.93 ± 14.42) ％ ( 11.24％ - 63.41％ ). However, the collagen proportionate area of hepatic fibrosis varied up to fivefold at decompensated cirrhotic stage. Conclusion The colla gen proportionate area at the decompensated cirrhosis stage was significantly increased, the maximum collagen proportionate area was 63.41％. The density and distribution of fibrosis are also important factors of cirrhosis.关键词
肝炎,乙型,慢性/肝硬化/图像解释,计算机辅助Key words
hepatitis B, chronic/ liver cirrhosis/ image interpretation, computer- assisted分类
医药卫生引用本文复制引用
马超,谢仕斌,李学俊,柯伟民,高志良..数字图像测定失代偿期乙型肝炎肝硬化肝组织纤维面积比例[J].临床肝胆病杂志,2011,27(8):833-836,4.基金项目
广东省科技计划项目(2009B030801006) （2009B030801006）
