临床肝胆病杂志2011，Vol.27Issue(8)：885-887,3.
丙型肝炎病毒抗体依赖性增强作用的研究现状及意义
The present research situation and significance of HCV ADE
摘要
Abstract
Antibody- dependent enhancement(ADE) is a phenomenon in the process of virus infection which refers to the virus -specific antibodies which can help or facilitate virus to enter the target cells. These antibodies have double effects, which are balanced between protection effects or enhancement effects of infection according to different antibody concentration. ADE is observed in many virus infection processes, moreover, the conventional vaccine usually has no effect to prevent or treat them. In this review, we discuss the mechanism of ADE in HCV infection, aiming to provide some new thoughts for HCV pathogenesis study, therapy and vaccine research.关键词
肝炎病毒属/受体,Fc/受体,补体Key words
hepacivirus/ receptors, Fc/ receptors, complement分类
医药卫生引用本文复制引用
高禄化,聂青和..丙型肝炎病毒抗体依赖性增强作用的研究现状及意义[J].临床肝胆病杂志,2011,27(8):885-887,3.基金项目
国家自然科学基金资助项目(No:30771891) （No:30771891）
