中国美容医学2011，Vol.20Issue(z3)：70-71,2.
小儿心脏手术麻醉期间空气混合氧(Fi020.5)改善气体交换
Oxygen in air (FiO20.5) improves gas exchange in congenital heart disease children during general anesthesia
鞠吉峰 1裴建民 2乔彬 1吴莉莉 1蒋怡燕 1徐军1
作者信息
- 1. 济南军区心血管病研究所,济南250000
- 2. 第四军医大学生理教研室
- 折叠
摘要
Abstract
Purpose: One hundred percent O2 is used routinely for preoxygenation and induction of anesthesia. The higher the O2 concentration the faster is the development of atelectssis, an important cause of impaired pulmonary gas exchange during general anesthesia (GA). We evaluated the effect of ventilation with 0. 5 FiO2 in air and 100％ O2 following intubation on the development of impaired gas exchange. Methods: One hundred and two patients aged 1 month - 15 yr, undergoing cardiac surgical intervention for congenital heart disease(non- cyanosis ) were administered 100％ O2 for preoxygenation (three minutes) and ventilation by mask ( two minutes). Following intubation these patients were randomly divided into two groups of and ventilated either with0.5 FiO2 in air of 49 cases or 100％ O2 of 53 cases. Which in before preoxygenation 、30 min following intubation 、entering ICU、after extubation 30min and three days of postoperation, afterial blood gases were obtained for analysis. Subsequently PaO2/FiO2 ratios were calculated. Results were analyzed with Student's t test and one - way ANOVA. P value of ＜ or = 0.05 was considered significant. Results: PCO2 value in entering ICU (C) that was significantly improved 0. 5 FiO2 group than 100％ O2 group. PaO2 value in entering ICU(C) and after extubation 30min(D) that were significantly improved 0.5 FIO2 group than 100％ O2 group. PaO2/FiO2 ratio value of 0.5 FiO2 group were more improved in after intubation 30min(B), in entering ICU(C) and after extubation 30min(D). Ventilation of the lungs with O2 in air0.5 FiO2 significantly improved the PaO2/FiO2 ratio(P ＜ 0.05). Conclusion: In cardiac surgical intervention for congenital heart disease (non - cyanosis ) children during GA, ventilation of lungs with O2 in air0.5 FiO2 was significantly improved gas exchange than in 100％ O2.关键词
肺不张/气体交换/麻醉/肺分流/氧Key words
Atelectasis/gas exchange/anesthesia/ polmonary shunt/ oxygen.分类
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鞠吉峰,裴建民,乔彬,吴莉莉,蒋怡燕,徐军..小儿心脏手术麻醉期间空气混合氧(Fi020.5)改善气体交换[J].中国美容医学,2011,20(z3):70-71,2.
