中国感染控制杂志2011，Vol.10Issue(3)：175-177,197,4.
纤维支气管镜下沐舒坦肺泡灌洗对重症脑卒中患者肺部感染的疗效
Effect of mucosolvan bronchoalveolar lavage on stroke patients with pulmonary infection
摘要
Abstract
Objective To evaluate the effect of mucosolvan bronchoalveolar lavage on stroke patients with pulmonary infection.Methods Forty-two stroke patients with pulmonary infection were randomly divided into two groups, normal saline group and mucosolvan group were 21 cases respectively.All patients were treated with antiinfection, bronchodilatation, aerosol inhalation and intravenous drip of mucosolvan in ICU.Observed indicators included acute physiological and chronic health evaluation (APACHE Ⅱ ) score, Glasgow coma scale (GCS) ,C-reaction protein (CPR), and clinic pulmonary infection score (CPIS) in all cases.The number of alveolar lavage , the average duration of lavage, aspirated sputum volume, the days in ICU, duration of using ventilators and CPIS were compared before and after lavage between two groups.Results There were no significant difference in age, gender,GCS score, APPACHE Ⅱ score and CRP before lavation in both groups(P＞0.05), and there was also no statistical difference in lavage number, average duration of lavage, and aspirated sputum volume between two groups (P = 0.05) ; mucosolvan group had less time on the ventilator ( [63.57 ± 21.94]h )and less day to stay in ICU([6.24 ± 1.04]d) than saline group([88.24 ± 21.35]h, [7.95 ± 1.36]d, respectively) (t = - 3.69, P = 0.00; t = - 4.58, P = 0.00) ; at the 3rd and 4th day after lavage , CPIS in mucosolvan group was (2.36 ± 0.77) and ( 2.17 ± 0.81) respectively, which were significantly lower than saline group([4.16 ± 0.86], [3.54 ± 1.09], respectively) (t = 3.60,P = 0.00 ; t = 2.25, P = 0.03).Conclusion Mucosolvan bronchoalveolar lavage can promote stroke patients to recover from pulmonary infection.关键词
肺泡灌洗/沐舒坦/纤维支气管镜/脑卒中/肺炎/祛痰Key words
bronchoalveolar lavage /mucosolvan/ fiberbronchoscope/ stroke/ pneumonia/expectorating分类
医药卫生引用本文复制引用
李志庆,曹国灿,张磊,彭璞,周伟,谢菊生..纤维支气管镜下沐舒坦肺泡灌洗对重症脑卒中患者肺部感染的疗效[J].中国感染控制杂志,2011,10(3):175-177,197,4.基金项目
湖南省郴州市科技局社会发展计划项日(2010 gl 31) （2010 gl 31）
