中国骨伤2011，Vol.24Issue(7)：616-620,5.DOI:10.3969/j.issn.1003-0034.2011.07.026
诱导多潜能干细胞治疗脊髓损伤的研究现状与进展
Current situation and progression of induced pluripotent stem cells in treating spinal cord injury
刘威 1张绍昆 1闫明 1刘理迪1
作者信息
- 1. 吉林大学第一临床医院脊柱外科,吉林长春130021
- 折叠
摘要
Abstract
Spinal cord injury is a difficult medical problem and current therapeutic methods could not obtain satisfactory results. Recent 20 years, stem cell technology developed rapidly, embryonic stem cells and adult stem cells were used for treating neurological disease and nerve injury of animal models and the clinical results were confirmed. It provided a new prospect for the treatment of nerve injury at the cellular level. However ,due to technical and ethical problems, it is difficult to obtain the appropriate cells that can be applied to the human being. Recently,induced pluripotent stem cells were developed as a new method for the treatment of spinal cord injuries by the autologous transplantation. Starting from this work,the purpose of this review is to assess the differentiate ability of induced pluripotent stem cells into neurocyte and review the latest developments in this area.关键词
多潜能干细胞/脊髓损伤/细胞移植/综述文献Key words
Pluripotent stem cells/ Spinal cord injuries/ Cell transplantation/ Review literature引用本文复制引用
刘威,张绍昆,闫明,刘理迪..诱导多潜能干细胞治疗脊髓损伤的研究现状与进展[J].中国骨伤,2011,24(7):616-620,5.
