中国康复理论与实践2011，Vol.17Issue(8)：745-747,3.
二苯乙烯对2型糖尿病大鼠降血糖作用的实验研究
Effect of Stilbene on Lowering Blood Glucose of Rats with Type 2 Diabetes
摘要
Abstract
Objective To study the effect of stilbene on blood glucose of rats with type 2 diabetes. Methods 50 male Wistar rats were randomly divided into model group (n=40) and control group (n=10). The model group was given fat emulsion 40 days continuously with 20m1/kg, po, and streptozotocin with 120 mg/kg on the 41st day, 100 mg/kg on the 42nd day, i.p. After the modeling, the model group was divided into 4 groups with 10 in each. They were given stilbene with 500 ml/kg, 200 ml/kg, 100 ml/kg and metformin with 100 mg/kg, ip, respectively. The level of blood glucose, blood lipid and glycogen content were determined. Results After the modeling, the blood glucose and TG, TC, LDL-C, HDL-C increased by 140.89％, 25.77％, 275.52％, 105.54％ and 31.25％ respectively (P＜0.01); after stilbene was given, the level of blood glucose and lipid decreased significantly (P＜0.05), the liver glycogen content increased significantly by 8.06％～16.17％ compared to the control group. Conclusion Stilbene can decrease the concentration of blood glucose and lipid, and increase the liver glycogen content of rats with type 2 diabetes.关键词
二苯乙烯/2型糖尿病/血糖/血脂Key words
stilbene/ type 2 diabetes/ blood glucose/ lipid分类
医药卫生引用本文复制引用
杨青平,俞发荣,车红霞,张梅,胡瑞萍,王擒虎,石磊..二苯乙烯对2型糖尿病大鼠降血糖作用的实验研究[J].中国康复理论与实践,2011,17(8):745-747,3.基金项目
甘肃省自然科学基金项目(0803RJZA052) （0803RJZA052）
甘肃省证据科学技术研究与应用重点实验室(培育基地)科技计划项目((ZDSYS-Y17). （培育基地）
