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以化学成分指纹图谱表征的川芎炮制及其汤剂成分研究

刘洋 梁吉春 石任兵 刘斌 姜艳艳

北京中医药大学学报2009,Vol.32Issue(10):699-701,3.
北京中医药大学学报2009,Vol.32Issue(10):699-701,3.

以化学成分指纹图谱表征的川芎炮制及其汤剂成分研究

Processing methods and composition study of slices and decoction of Rhizoma Chuanxiong characterized by chemical composition fingerprint

刘洋 1梁吉春 1石任兵 1刘斌 1姜艳艳1

作者信息

  • 1. 北京中医药大学中药学院,北京,100102
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摘要

Abstract

Objective To investigate the influences of common preparation methods of slices of Rhizoma Chuanxiong on the changes of their chemical compositions by applying fingerprint chromatogram, and their dissolution characteristics in the decoction of the slices of Rhizoma Chuanxiong after exacting for different times. Methods The changes of chemical compositions of the slices, and difference between extractable compositions and original compositions of Rhizoma Chuanxiong were compared before and after the preparation by applying HPLC fingerprint chromatogram and the control and analytic method of chemical standard samples. Results The chemical compositions of the slices was not much different from original compositions after preparation. The liposoluble compositions of the slices was dissolved less in the decoction, while the most of water-soluble compositions were extracted out after extracting for three times. Conclusion When the slices of Rhizoma Chuanxiong were decocted alone, less liposoluble compositions are dissolved in decoction, which indicates that the effective material base ( chemical compositions) of the slices of Rhizoma Chuanxiong in decoction should be water-soluble compositions.

关键词

川芎/炮制/汤剂/化学成分/高效液相色谱/指纹图谱

Key words

Rhizoma Chuanxiong/ processing/ decoction/ chemical compositions/ HPLC/ fingerprint chromatogram

分类

医药卫生

引用本文复制引用

刘洋,梁吉春,石任兵,刘斌,姜艳艳..以化学成分指纹图谱表征的川芎炮制及其汤剂成分研究[J].北京中医药大学学报,2009,32(10):699-701,3.

北京中医药大学学报

OA北大核心CSCDCSTPCD

1006-2157

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