南方医科大学学报2009,Vol.29Issue(10):2024-2026,3.
胚胎皮肤细胞裸鼠皮下移植构建毛发发育模型
Subcutaneous implantation of embryonic skin cells to construct a model of hair development in nude mice
摘要
Abstract
Objective To observe the hair development after subcutaneous implantation of embryonic skin cells in nude mice, and construct a model of hair development. Methods Dermal and epidermal cells isolated from embryonic mouse skin were mixed at a given ratio and injected subcutaneously in nude mice, and hair formation after the implantation was observed under a microscope. Results Formation of the hair follicles and fibers under the skin of the recipient nude mice and emergence of the hair shaft were observed microscopically. Conclusion Embryonic skin cells be used to construct a complete model of hair development after implantation in vivo.关键词
胚胎皮肤/细胞移植/毛发发育模型Key words
embryonic skin/ cell implantation/ hair development model分类
医药卫生引用本文复制引用
陈明娟,胡志奇,谭挺,孙锡金,苗勇..胚胎皮肤细胞裸鼠皮下移植构建毛发发育模型[J].南方医科大学学报,2009,29(10):2024-2026,3.基金项目
国家自然科学基金(30872692) (30872692)
广东省自然科学基金(8151051501000037) (8151051501000037)
广州市科技计划项目(2007Z3-E002i) (2007Z3-E002i)