南方医科大学学报2009，Vol.29Issue(10)：2007-2009,3.
彩色多普勒超声、超声造影及CA-125对卵巢病变的鉴别诊断价值
Value of color Doppler ultrasonography, contrast-enhanced ultrasound and serum CA-125 detection in differential diagnosis of ovarian masses
摘要
Abstract
Objective To assess the value of color Doppler ultrasonography, contrast-enhanced ultrasound and detection of serum CA-125 levels in the differential diagnosis of ovarian masses. Methods The findings of color Doppler ultrasonography, contrast-enhanced ultrasound and the serum levels of CA-125 were comparatively analyzed in 65 patients with ovarian masses, and the diagnostic accuracy of the 3 methods was estimated. Results Of the 65 cases of ovarian masses, 21 of the 35 patients with benign ovarian masses had serum CA-125 levels below 35 U/ml, and 28 of the 30 patients with malignant masses showed CA-125 levels over 35 U/ml. Color Doppler ultrasonography identified 30 benign and 22 malignant cases, but failed to produce definite results in 13 cases (including 5 with benign and 8 with malignant masses). By contrast-enhanced ultrasound, benign masses were found in 34 cases and malignant masses in 29 cases, and misdiagnosis occurred in 2 cases (including 1 case of thecoma and 1 of ovarian borderline tumor). With serum CA-125 detection, color Doppler ultrasonography and contrast-enhanced ultrasound, the diagnostic sensitivity for ovarian masses was 66.7%, 73.3%, and 96.7%, and the specificity was 60.0%, 85.7%, and 97.1%, respectively. Conclusions Detection of serum CA-125 level and ultrasound examinations help in the diagnosis and differential diagnosis of benign and malignant ovarian masses. Compared with serum CA-125 detection and color Doppler ultrasonography, contrast-enhanced ultrasound is more informative on perfusion patterns of the ovarian masses to result in higher accuracy in early and differential diagnosis of the ovarian masses.关键词
卵巢病变/彩色多普勒超声/超声造影/血清CA-125Key words
ovarian mass/ color Doppler sonography/ contrast-enhanced ultrasound/ serum CA-125分类
医药卫生引用本文复制引用
周琦,刘百灵,姜珏,雷小莹..彩色多普勒超声、超声造影及CA-125对卵巢病变的鉴别诊断价值[J].南方医科大学学报,2009,29(10):2007-2009,3.基金项目
陕西省科技攻关项目2008K09-08(1) （1）
