华北农学报2009,Vol.24Issue(5):45-49,5.
类猪圆环病毒因子P1 VP2蛋白二级结构与B细胞表位预测
Prediction of Secondary Structure and B Cell Epitope for VP2 Protein of Porcine Circovirus-like Agent P1
摘要
Abstract
To predict the B cell epitopes for VP2 protein of porcine circovirus-like agent PI. By using biotic soft-wares and network servers,the secondary structure of VP2 was predicted,and the surface properties (hydrophilicity,flexi-bility ,accessibility and antigenicity) of VP2 were analysed.Then the B cell epitopes integrated prediction were obtained. The predominant B cell epitopes predicted were probably in the region of 6 - 18 and 80 - 92.The results of B cell epi-topes prediction using multiple parameters are helpful for further epitopes identification and vaccine design of P1.关键词
P1/二级结构/B细胞表位/生物信息学/预测Key words
P1/ Secondary structure /B cell epitope/Bioinformatics/ Prediction分类
农业科技引用本文复制引用
温立斌,何孔旺,杨汉春,王玉然..类猪圆环病毒因子P1 VP2蛋白二级结构与B细胞表位预测[J].华北农学报,2009,24(5):45-49,5.基金项目
国家"973"计划前期研究专项(2007CB116308) (2007CB116308)
江苏省自然科学基金(BK2008351) (BK2008351)