山西大学学报(自然科学版)2009,Vol.32Issue(3):451-454,4.
以模型化合物方法对铜离子与Aβ肽的配位模式的初步研究
A Preliminary Study on the Coordination Modes Between Cu(Ⅱ) ion and β-Amyloid Peptide with the Method of Model Compounds
摘要
Abstract
Coordination modes between Cu(II) ion and β-amyloid peptide(Aβ) were studied by syntheses of model complexes to mimic the coordination environments. On the basis of crystal data and electronic spectra data of the model complexes,it was that N2O2 coordination mode might not be the proper coordination mode between Cu(II) ion and β-amyloid peptide.关键词
老年痴呆症/Aβ肤/铜离子/模型化合物/配位模式Key words
alzheimer's disease/β- amyloid peptide (Aβ)/Cu(II) ion/model compounds/ coordination modes分类
化学化工引用本文复制引用
张志刚,马旭艳,姚秀杰..以模型化合物方法对铜离子与Aβ肽的配位模式的初步研究[J].山西大学学报(自然科学版),2009,32(3):451-454,4.基金项目
国家自然科学基金(30470408) (30470408)
山西省回国留学人员科研资助项目 ()