中国组织工程研究与临床康复2009，Vol.13Issue(42)：8337-8340,4.DOI:10.3969/j.issn.1673-8225.2009.42.031
白色念珠菌在义齿软衬材料表面黏附的研究与进展
Adherence of Candida albicans to the surface of soft lining materials
摘要
Abstract
OBJECTIVE: To analyze the influencing factor of Candida albicans adhered to soft lining materials surface, and to find the main prevention and cure methods. DATA SOURCE: The relevant articles between 1995 and 2009 were retrieved from PubMed (http://www.ncbi.nlm.nih.gov/PubMed) and database of Chinese knowledge (CNKI www.cnki.net/index.htm) using key words of "denture, soft lining material, Candida albicans, and adherence", and restricting the language as English and Chinese by computer. DATA SELECTION: The original articles with representation in the materials or methods were included. Repetitiveness or unrelated papers were excluded. MAIN OUTCOME MEASURES: The influencing factor of Candida albicans adhered to soft lining materials surface, as well as the main prevention and cure methods. RESULTS: ①The materials of dentures had certain effect on Candida albicans adherence, in using, plasticizer and ethanol would separate from acrylics soft-lining materials, which could result in dentures failure. Silicon rubber soft-lining materials exhibited good biocompatibility with little cytotoxicity, but the porosity easy lead to fungi propagation. The water absorption of materials containing fluorine was lower than silicon rubber materials with lower fungi propagation. ②The correlation between surface roughness or surface free energy of materials and Monilia adherence was uncertain. ③The formation of Candida albicans film was associated with saliva, substrate circumstances and symbiotic bacteria strains.④The main methods for preventing Candida albicans adherence was as following: adding antifungal agent in soft lining materials; selecting matched denture cleansing agents; treating surface of soft lining materials; antifungal agent treatment or microwave sterilization. CONCLUSION: Presently, the adherence of Candida albicans to surface of soft lining materials is still a common but serious problem. The denture stomatitis can be controlled by improving the performance of soft lining materials, reducing the adherence of microorganism, and prolonging useful life of dentures.关键词
义齿/软衬材料/白色念珠菌/黏附分类
基础医学引用本文复制引用
李苑,郭巍,李惠玲,高宁..白色念珠菌在义齿软衬材料表面黏附的研究与进展[J].中国组织工程研究与临床康复,2009,13(42):8337-8340,4.基金项目
四川省科技厅支持项目(2008SG0023) （2008SG0023）
珠海市科技局科技项目(PC2008 1039) （PC2008 1039）
