应用化学2009，Vol.26Issue(12)：1409-1413,5.
苯并呋喃酮衍生物结构对其DPPH捕获能力的影响
Structural Effect of Benzofuranone Derivatives on the Scavenging Ability for 2,2-Diphenyl-1-picrylhydrazl
摘要
Abstract
The structural effect of benzofuranone derivatives on their ability to scavenge 2,2-diphenyl-1-picrylhydrazl(DPPH) was studied via radical colorimetry. The results show that the changes of methyl and tert-butyl groups on 5 and 7 positions of mother benzene ring of benzofuranone and the presence of strong electron-donating substituent in substituted benzene ring have little influences on the ability of benzofuranone derivatives scavenging DPPH. Substituent of 2′-position prevents the attack of benzofuranone toward radicals, which weak the scavenging ability of benzofuranone derivatives for DPPH. And the scavenging ability of benzofuranone for DPPH will be weakened further when the substituent of 2′-position is without reactive hydrogen and can form hydrogen bonds with 3-reactive hydrogen. When the substituent of 2′-position is with reactive hydrogen, the reactive hydrogen will be activated due to the formation of hydrogen bonding between substituted group with 3-reactive hydrogen, and the position hindrance will be generated in a great extent.关键词
DPPH/苯并呋喃酮/抗氧性能/自由基捕获能力Key words
DPPH/benzofuranones/antioxidant activity/scavenging ability分类
化学化工引用本文复制引用
孟鑫,周长路,辛忠..苯并呋喃酮衍生物结构对其DPPH捕获能力的影响[J].应用化学,2009,26(12):1409-1413,5.基金项目
2008年国家青年科学基金(20806023)、2007年华东理工大学优秀青年教师基金(YA0157107)资助项目 （20806023）
