应用化学2009，Vol.26Issue(10)：1159-1164,6.
新型含氟Philanthotoxin-12衍生物的无溶剂4组分Ugi反应合成及杀虫活性
Solvent-free Ugi Four-component Synthesis and Insecticidal Activities of Novel Fluorine-Containing Philanthotoxins-12 Derivatives
摘要
Abstract
Eight novel fluorine-containing PhTX-12 derivatives were prepared from the intermediate obtained via one-pot Ugi four-component solvent-free reactions by the simple removal of the protecting groups in the presence of trifluoroacetic acid. Their structures were identified by ~1H NMR, ~(13)C NMR and HRMS or MS. Preliminary bioassays indicate that compound 6b showed 44% and 42% mortality rates against Heliothis armigera and Pieris rapae respectively at a concentration of 100 mg/L.关键词
Philanthotoxin/无溶剂合成/4组分Ugi反应/杀虫活性Key words
Philanthotoxin/solvent-free synthesis/Ugi 4-CR/insecticidal activity分类
化学化工引用本文复制引用
刘年金,曹松,马严明,申丽,钱旭红..新型含氟Philanthotoxin-12衍生物的无溶剂4组分Ugi反应合成及杀虫活性[J].应用化学,2009,26(10):1159-1164,6.基金项目
国家重点基础研究发展规划"九七三"项目(2003CB114405) （2003CB114405）
