针刺研究2009,Vol.34Issue(5):344-348,5.
针挑与牵旋手法对椎动脉型颈椎病血流的影响及机制研究
Influence of Needle-pricking Bleeding Combined with Pulling-rotating Manipulation on Blood Rheology in Patients with Vertebral Artery Type Cervical Spondylosis
摘要
Abstract
Objective To observe the effect of needle-pricking bleeding combined with pulling-rotating manipulation and simple manipulation on blood rheology in vertebral artery type cervical spondylosis (VATCS) patients, so as to analyze their mechanisms in relieving VATCS. Methods A total of 198 VATCS patients were randomly divided into treatment group (n = 101) which was treated with needle-pricking plus pulling-rotating manipulation, and control group (n = 97) which was treated with simple pulling-rotating manipulation, according to the random number table. The treatment was given once every 7 days, 9 times altogether. The peak systolic blood flow velocity (V_(peak)), end-diastolic blood velocity (V_(min)), pulsatility index (PI) and resistent index (Rl) of bilateral vertebral arteries (V_A) and basilar artery (B_A) were detected by transcranial doppler sonography (TCD). Whole blood apparent viscosity and the plasma viscosity in the treatment group were determined by using a blood viscosimeter. Results Of the 101 and 97 VATCS cases in the treatment and control groups, 62(61. 38%) and 12(12. 37%) were cured basically, 23(22. 77%) and 26(26. 80%) experienced marked improvement, 14(13. 86%) and 41 (42. 27%) were improved, 2(1. 98%) and 18(18. 55%) failed in the treatment, with the total effective rates being 98. 01% and 81. 44% separately. The effective rate of the treatment group was significantly higher than that of control group (P<0. 05). Compared with pretreatment, V_(peak) and V_(min) of the bilateral V_A and B_A in the treatment group, and V_(peak) of the right V_A in the control group increased significantly (P<0. 01, P<0. 05), PI and Rl of the bilateral V_A and B_A in the treatment group, and PI and Rl of the right V_A in the control group decreased significantly (P<0. 01, P<0. 05), suggesting a marked reduction of the vascular resistance and an apparent increase of the cerebral blood supply after the treatment. The therapeutic effects of the above-mentioned indexes of treatment group were significantly superior to those of the control group (P<0. 05). In comparison with pre-treatment, the whole blood apparent viscosity (high, medium and low shear rates) and plasma viscosity of the treatment group post-treatment were obviously reduced (P<0. 01. P<0. 05). Conclusion Needle-pricking therapy combined with pulling-rotating manipulation can significantly improve VATCS patients' clinical symptoms, which may be closely related to its effects in lowering vascular blood resistance and blood viscosity and increasing cerebral blood supply.关键词
椎动脉型颈椎病/针挑/扳法/经颅多普勒超声Key words
Vertebral artery type cervical spondylosis/ Needle-pricking therapy/ Pulling-rotating manipulation/ Transcranial Doppler sonography分类
医药卫生引用本文复制引用
陈栋,钟键,洪衍波,陈大典,邓列华,蔡明雪,章岳娟,林秀华,郑富仕..针挑与牵旋手法对椎动脉型颈椎病血流的影响及机制研究[J].针刺研究,2009,34(5):344-348,5.基金项目
暨南大学自然科学研究基金资助(99046) (99046)