中国临床药理学与治疗学2009，Vol.14Issue(2)：191-194,4.
还原型谷胱甘肽对酒精性肝炎患者肝纤维化指标的影响
Reduced glutathione hormone's impact on alcoholic hepatitis patient's index of hepatic fibrosis
周红萍 1庄让笑 1茹仁萍1
作者信息
- 1. 杭州市第六人民医院药剂科,杭州,310014,浙江
- 折叠
摘要
Abstract
AIM: To observe the changes of hepatic fibrosis index, clinical symptom, physical sign and hepatic function after the patients were treated treatment with reduced glutathione hormone. METHODS: The 72 patients were divided into two groups that one was the treatment group with 37 patients and the other was the control group with 35 patients. The control group was accepted the treatment with Ganlixin Injection, Magnesium Aminosuccinate Injection and Mulvi-tal, etc. The treatment group was accepted reduced glutathione hormone (1.5 g, once a day) in addition. The course of treatment lasted for 8 weeks. We observed the two groups' blood-serum fibrosis indexes (HA, LN, PIII-P, C-IV)and biochemistry indxes (TBIL, ALT, AST, GGT) before and after the treatment. RESULTS: The improvements of the treatment group were much better than the control group on the sides of clinical symptom, physical sign, hepatic function and blood-serum fibrosis. The treatment group's blood-serum fibrosis indexes were much lower after the treatment (P < 0.01), and there was no clear decline in the control group. There were obvious differences between the two groups(P < 0.01). CONCLUSION: holic hepatitis; hepatic fibrosis Reduced glutathione hormone has the significant effects of anti-fibrosis and liver protection.关键词
还原型谷胱甘肽/酒精性肝炎/肝纤维化Key words
reduced glutathione hormone/ alco分类
医药卫生引用本文复制引用
周红萍,庄让笑,茹仁萍..还原型谷胱甘肽对酒精性肝炎患者肝纤维化指标的影响[J].中国临床药理学与治疗学,2009,14(2):191-194,4.
