中国实用儿科杂志2009，Vol.24Issue(11)：866-868,3.
难治性癫痫83例临床分析
Clinical analysis of 85 cases of refractory epilepsy
高萱 1周水珍1
作者信息
- 1. 复旦大学附属儿科医院,上海,201102
- 折叠
摘要
Abstract
Objective To identify the clinical features of refractory epilepsy (RE) for an early diagnosis. Methods The children with epilepsy(n = 400)were retrospectively or prospectively identified from multiple sources in our hospital in Shanghai(2006-2008)and followed-up for the occurrence of refractory epilepsy. ILAE definitions and classifications were used. Results The average follow-up was 0.96 years. Totally 83 children (20.8%) met the criteria for RE, including 64(77.1%) symtomatic and 19(22.9%) cyptogenic. Sixty-one(73.5% ) had high seizure frequecy(with seiz-wres per day or week), and 43 (51.8%) had multiple seizure types. Thirty-seven children had positive lesion in neuro-imaging, 26 had slow EEG background, and 18 had focal spikes. About 50.6% children used three AEDs , and 7.2% used four. Conclusion The features of RE in children are early age at onset, high initial frequency, being mostly symptomatic, with or secondary with mental retardation, neuroimaging abnormity, slow EEG background and poor treatment effect using multiple AEDs.关键词
难治性癫痫/儿童/临床特点Key words
refractory epilepsy/children/clinical feature分类
医药卫生引用本文复制引用
高萱,周水珍..难治性癫痫83例临床分析[J].中国实用儿科杂志,2009,24(11):866-868,3.
