中国兽医科学2009,Vol.39Issue(11):999-1002,4.
鸡盲肠扁桃体中B淋巴细胞的发育
Development of B lymphocytes in caecal tonsil of chicken
摘要
Abstract
The occurrence,migration,tissue localization and quantity changes of IgM~+, IgG~+ and IgA~+ B lymphocytes in chicken caecal tonsil were examined using the IgM, IgG and IgA monoclonal antibodies by immunohistochemical method. The results showed that IgM~+ cells first appeared in caecal tonsil from em-bryonic on day 20, both IgG~+ and IgA~+ cells appeared at 1-day-old. B lymphocytes mainly distributed in lamina propria under epithelium before 4-day-old; B lymphocytes were mainly distributed in middle and su-perior part mucous layer, whereafter they uniformly distributed in the whole mucous layer. The germinal centers which were composed by B lymphocytes appeared in the lamina propria at 14-day-old, but clear-cut germinal centers resided in the middle and inferior part of lamina propria at 21-day-old,and there were nu-merous IgM~+, IgG~+ and IgA~+ cells in germinal centers. B lymphocytes kept increasing with the increase of age,and reached stable at 35-day-old. Among the three type cells,IgM~+ cells were the most and IgG~+ cells were the least all the time. The results confirmed that the humoral immune function of caecal tonsil in chicken strengthened quickly after hatching,and reached the mature level at 35-day-old.关键词
鸡/盲肠扁桃体/B淋巴细胞/发育Key words
chicken/ caecal tonsil/ B lymphocyte/ development分类
农业科技引用本文复制引用
杨树宝,张英楠,高晶晶,张延林,杨丽华,栾维民..鸡盲肠扁桃体中B淋巴细胞的发育[J].中国兽医科学,2009,39(11):999-1002,4.基金项目
国家自然科学基金项目(30771557) (30771557)
吉林农业大学青年启动基金项目(2009) (2009)