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鸡盲肠扁桃体中B淋巴细胞的发育

杨树宝 张英楠 高晶晶 张延林 杨丽华 栾维民

中国兽医科学2009,Vol.39Issue(11):999-1002,4.
中国兽医科学2009,Vol.39Issue(11):999-1002,4.

鸡盲肠扁桃体中B淋巴细胞的发育

Development of B lymphocytes in caecal tonsil of chicken

杨树宝 1张英楠 2高晶晶 3张延林 4杨丽华 2栾维民1

作者信息

  • 1. 吉林农业大学动物科学技术学院,吉林,长春,130118
  • 2. 吉林农业大学,发展学院,吉林,长春,130600
  • 3. 天津瑞普高科生物药业有限公司,天津,300380
  • 4. 北京昭衍新药研究中心有限公司,北京,100176
  • 折叠

摘要

Abstract

The occurrence,migration,tissue localization and quantity changes of IgM~+, IgG~+ and IgA~+ B lymphocytes in chicken caecal tonsil were examined using the IgM, IgG and IgA monoclonal antibodies by immunohistochemical method. The results showed that IgM~+ cells first appeared in caecal tonsil from em-bryonic on day 20, both IgG~+ and IgA~+ cells appeared at 1-day-old. B lymphocytes mainly distributed in lamina propria under epithelium before 4-day-old; B lymphocytes were mainly distributed in middle and su-perior part mucous layer, whereafter they uniformly distributed in the whole mucous layer. The germinal centers which were composed by B lymphocytes appeared in the lamina propria at 14-day-old, but clear-cut germinal centers resided in the middle and inferior part of lamina propria at 21-day-old,and there were nu-merous IgM~+, IgG~+ and IgA~+ cells in germinal centers. B lymphocytes kept increasing with the increase of age,and reached stable at 35-day-old. Among the three type cells,IgM~+ cells were the most and IgG~+ cells were the least all the time. The results confirmed that the humoral immune function of caecal tonsil in chicken strengthened quickly after hatching,and reached the mature level at 35-day-old.

关键词

/盲肠扁桃体/B淋巴细胞/发育

Key words

chicken/ caecal tonsil/ B lymphocyte/ development

分类

农业科技

引用本文复制引用

杨树宝,张英楠,高晶晶,张延林,杨丽华,栾维民..鸡盲肠扁桃体中B淋巴细胞的发育[J].中国兽医科学,2009,39(11):999-1002,4.

基金项目

国家自然科学基金项目(30771557) (30771557)

吉林农业大学青年启动基金项目(2009) (2009)

中国兽医科学

OA北大核心CSCDCSTPCD

1673-4696

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