摘要
Abstract
To probe into the reasons behind the overanticoagulation and underanticoagulation in patients receiving warfarin, METHODS: 95 patients hospitalized in our hospital from Jan. to Sept. in 2008 were analyzed in respect of patients' age, gender, weight, dosage of warfarin, international normalized ratio(INR), anticoagulation state, drug combination, etc. RESULTS: Patients' age and weight were correlated to the dosage and anticoagulative effect of warfarin, Levofloxacin was the most potent in enhancing the anticoagulative effect of warfarin. Of the 480 times of INR monitoring, the INR of 332 (69.2 %) were within 2.0～3.0, and bleeding was noted in 7 cases (7.4 %). CONCLUSION: The anticoagulative effect of warfarin is associated with many factors; therefore, it is urgent to tighten anticoagulative monitoring.关键词
华法林/抗凝/国际标准化比值Key words
Warfarin/ Anticoagulation/ International normalized ratio分类
医药卫生
