中华医学杂志（英文版）2009，Vol.122Issue(20)：2433-2437,5.DOI:10.3760/cma.j.issn.0366-6999.2009.20.007
Dysembryoplastic neuroepithelial tumors: magnetic resonance imaging and magnetic resonance spectroscopy evaluation
Dysembryoplastic neuroepithelial tumors: magnetic resonance imaging and magnetic resonance spectroscopy evaluation
YU Ai-hong 1CHEN Li 1LI Yong-jie 1ZHANG Guo-jun 1LI Kun-cheng 1WANG Yu-ping1
作者信息
- 1. Xuanwu Hospital,Capital Medical University
- 折叠
摘要
Abstract
Background Dysembryoplastic neuroepithelial tumor (DNT) is a rare benign neoplasm of the central nervous system affecting young people. A correct preoperative diagnosis is helpful for planning surgical strategies and improving prognosis. The purpose of this study was to characterize DNTs using magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) and to analyze the value of these two techniques in the diagnosis of DNTs.Methods MR images of 13 patients with DNTs were reviewed retrospectively; and five of the patients also underwent MRS. Tumors were confirmed by surgery. The distribution, extension and signal features of the lesions were assessed,and the MRS results were analyzed.Results All tumors were supratentorial. The cortex was the main area involved, with nine tumors located in the temporal lobe, three in the frontal lobe, and one on the boundary between the temporal and occipital lobes. All cases had decreased signal intensity on T1-weighted MR images and increased signal intensity on T2-weighted images. On fluid attenuated inversion recovery weighted images, the hyperintense "ring sign" and internal septation of the lesion were seen in 9 cases. Eight tumors had well-demarcated borders. Peritumoral edema or mass effect was absent in all cases. A contrast enhancement examination was performed in 9 cases. Contrast enhancement was absent in five cases, and four cases showed significant enhancement. The MRS showed a low N-acetylaspartate peak and a lack of elevated choline-containing component (Cho) or Cho-Cr ratio (Cho/Cr) in five patients.Conclusions The MRI findings of DNTs were stereotypical. The combination of MRI and MRS techniques were helpful in making a correct presurgical diagnosis.关键词
epilepsy/ dysembryoplastic neuroepithelial tumor/ magnetic resonance imaging/ magnetic resonance spectroscopyKey words
epilepsy/ dysembryoplastic neuroepithelial tumor/ magnetic resonance imaging/ magnetic resonance spectroscopy分类
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YU Ai-hong,CHEN Li,LI Yong-jie,ZHANG Guo-jun,LI Kun-cheng,WANG Yu-ping..Dysembryoplastic neuroepithelial tumors: magnetic resonance imaging and magnetic resonance spectroscopy evaluation[J].中华医学杂志（英文版）,2009,122(20):2433-2437,5.
