首页|期刊导航|中华医学杂志（英文版）|A free-breathing non-contrast-enhanced pulmonary magnetic resonance angiography at 3 Tesla
中华医学杂志（英文版）2009，Vol.122Issue(18)：2111-2116,6.DOI:10.3760/cma.j.issn.0366-6999.2009.18.007
A free-breathing non-contrast-enhanced pulmonary magnetic resonance angiography at 3 Tesla
A free-breathing non-contrast-enhanced pulmonary magnetic resonance angiography at 3 Tesla
摘要
Abstract
Background The breathhold contrast-enhanced three-dimensional magnetic resonance angiography (MRA) using T1-weighted gradient-echo imaging sequence is the standard technique for MRA of the thorax. However, this technique is not desirable for certain patients with respiratory insufficiency, serious renal impairment, or allergy to contrast agents. The objective of this study was to optimize and evaluate a non-contrast-enhanced free-breathing pulmonary MRA protocol at 3 Tesla.Methods The time-of-flight protocol was based on a two-dimensional T1-weighted turbo field echo sequence with slice-selective inversion recovery and magnetization transfer preparation together with respiratory navigator gating, cardiac gating, and parallel imaging. Optimal values for time of inversion delay, flip angle and slice thickness were experimentally determined and used for all subjects.Results Excellent pulmonary MRA images, in which the 7th order branches of pulmonary arteries could be reliably identified, were obtained in the 12 free-breathing healthy volunteers. TI of ～300 ms provides the best suppression of background thoracic and cardiac muscles and effective inflow enhancement. With increasing flip angle, the pulmonary vessels gradually brightened and exhibited optimal contrast at 20°-30°. The 2 mm slice thickness and 0.5 mm slice overlap is suitable for visualization of the peripheral pulmonary vessel.Conclusions The MRA protocol at 3 Tesla may have clinical significance for pulmonary vascular imaging in patients who are not available for contrast-enhanced 3D MRA and CT angiography examination or are unable to sustain a long breath-hold.关键词
magnetic resonance angiography/ pulmonary/ blood vesselsKey words
magnetic resonance angiography/ pulmonary/ blood vessels引用本文复制引用
YANG Jian,WANG Wei,WANG Ya-rong,NIU Gang,JIN Chen-wang,WU Ed Xuekui..A free-breathing non-contrast-enhanced pulmonary magnetic resonance angiography at 3 Tesla[J].中华医学杂志（英文版）,2009,122(18):2111-2116,6.基金项目
This work was supported in part by grants from the National Natural Science Foundation of China (No.30200066), Ph.D.Programs Foundation of the Ministry of Education of China (No.2004069805) and Hong Kong Research Grant Council (No.GRF7794/07M). （No.30200066）
