质谱学报2009，Vol.30Issue(6)：374-378,5.
槲皮素的电喷雾离子阱质谱分析
Elucidation of Quercetin by Electron Spray Ionization Mass Spectrometry
摘要
Abstract
Positive and negative electron spray ionization mass spectrometry (ESI-MS) was used to analyse the chemical structure and MS/MS fragmentation pathway of quercetin.The positive ESI-MS characteristic ions and fragmentation mechanism of quercetin were elucidated and explained by the program of Mass Frontier 3.0. Fragment ions m/z 287, 285,275, 267, 257 and 229 are existed at the positive ion mode, and the fragment m/z 285 and 275 are further fragmented to form m/z 257 and 229. These ions are the fragmentation characteristics of quercetin in the positive ESI-MS. Fragment ions m/z 283, 273, 257, 245,229 are the fragmentation characteristics in negative ESI-MS, and the fragment m/z 255 is formed by m/z 283 or m/z 273. The fragmentation pathway in positive and negative ESI-MS is similar, but the negative ESI-MS mode provides less fragment ions. These results provide the very important information for the drug metabolic research and the structural modification of quercetin.关键词
槲皮素/电喷雾电离质谱(ESI-MS)/结构分析Key words
quercetin/ electron spray ionization mass spectrometry ( ESI-MS )/ structural elucidation分类
化学化工引用本文复制引用
李宇航,戴海学,汪明明,李晓蓉,王丽娟,薛明..槲皮素的电喷雾离子阱质谱分析[J].质谱学报,2009,30(6):374-378,5.基金项目
国家自然科学基金(30472057),北京市自然科学基金(7052007)暨北京市属高等学校人才强教计划资助项目(PHR2001007111) （30472057）
