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酪氨酸激酶抑制剂耐药机制及其治疗策略

乔建兵

中国肺癌杂志2011,Vol.14Issue(10):806-810,5.
中国肺癌杂志2011,Vol.14Issue(10):806-810,5.DOI:10.3779/j.issn.1009-3419.2011.10.07

酪氨酸激酶抑制剂耐药机制及其治疗策略

Resistant Mechanism and Treatment Strategy of Tyrosine Kinase Inhibitors

乔建兵1

作者信息

  • 1. 210029,南京,南京市胸科医院呼吸内科
  • 折叠

摘要

Abstract

Gestational choriocarcinoma is the most common gestational trophoblastic neoplasia. It is prone to hematogenous metastasis, most commonly to the lungs. With the advent and development of chemotherapy, choriocarcinoma has become a curable tumor. However, patients with drug-resistant and recurrent choriocarcinoma are difficult to treat, even with the management of pulmonary metastasis. Resorting to surgery is also a tough decision given the challenges of identify-ing the appropriate surgical indication and timing. This review discusses the basic principles of management as well as recent advances in the diagnosis and treatment of patients with pulmonary metastasis of gestational choriocarcinoma.

关键词

Gestational choriocarcinoma/ Pulmonary metastasis/ Diagnosis and treatment/ Surgical indication

Key words

Gestational choriocarcinoma/ Pulmonary metastasis/ Diagnosis and treatment/ Surgical indication

分类

医药卫生

引用本文复制引用

乔建兵..酪氨酸激酶抑制剂耐药机制及其治疗策略[J].中国肺癌杂志,2011,14(10):806-810,5.

中国肺癌杂志

OA北大核心CSTPCDMEDLINE

1009-3419

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