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肾移植术后隐球菌性脑膜炎合并肺炎1例并文献复习

祝藩原 张雷 朱有华 王立明

中国真菌学杂志2011,Vol.6Issue(4):32-35,4.
中国真菌学杂志2011,Vol.6Issue(4):32-35,4.

肾移植术后隐球菌性脑膜炎合并肺炎1例并文献复习

Cryptococcal meningitis complicated with pneumonia after kidney transplantation:one case report and literature review

祝藩原 1张雷 1朱有华 1王立明1

作者信息

  • 1. 第二军医大学长征医院器官移植中心,上海 200003
  • 折叠

摘要

Abstract

Objective To investigate the diagnosis and treatment of cryptococcal meningitis complicated with pneumonia after kidney transplantation. Methods One case of cryptococcal meningitis complicated with pneumonia after kidney transplantation was reported and related literatures were reviwed. Result The clinical symptoms (headache, nausea and vomiting, cough and expectoration etc) and the lung lesions in CT imaging disappeared after induction therapy with amphotericin B liposome and voriconazole and maintenance therapy with voriconazole. The acute rejection was abscent during the course of treatment. Conclusions As the clinical findings of kidney transplant recipients with cryptococcal meningitis complicated with pneumonia are non-specific, CSF india ink stain and latex agglutination test for cryptococcal antigen should be performed to establish an early diagnosis. Timely diagnosis and antifungal therapy are necessary of the prognosis. Immunosuppressive drugs should be adjusted depending the progress of antifungal therapy.

关键词

隐球菌性脑膜炎合并肺炎/肾移植/治疗

Key words

cryptococcal meningitis complicated with pneumonia/ kidney transplantation/ therapy

分类

医药卫生

引用本文复制引用

祝藩原,张雷,朱有华,王立明..肾移植术后隐球菌性脑膜炎合并肺炎1例并文献复习[J].中国真菌学杂志,2011,6(4):32-35,4.

中国真菌学杂志

OACSTPCD

1673-3827

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