中国实用外科杂志2011，Vol.31Issue(8)：703-704,2.
原位肝移植术后颅内出血原因和处理
Causes and treatment of intracranial hemorrhage after orthotopic liver transplantation
摘要
Abstract
Objective To investigate the clinical features and prophylactico-therapeutic measures of intracranial hemorrhage after orthotopic liver transplantation (OLT). Methods The clinical data of 638 patients after OLT between January 2004 and December 2008 at the First Affiliated Hospital of Sun Yat-Sen University were analyzed retrospectively. The accumulated experiences in diagnosis and treatment of postoperative intracranial hemorrhage after OLT were reviewed. Results Among the 638 patients, 10 patients (1.6%) suffered from intracranial hemorrhage. One patient happened within the first week after transplantation, 3 within 2 weeks, 6 within 4 weeks. Once the diagnosis is confirmed, dehydrative measures were taken immediately to decrease the intracranial pressure, and antibiotics were applied to control infection at the same time. Four patients underwent emergency craniotomy to clear the intracranial hematoma. Among 10 patients, 6 patients (60.0%) died. Conclusion Intracranial hemorrhage after OLT is extremely dangerous with high mortality. Common causes of postoperative intracranial hemorrhage should be well known. Once the patients show any sign of abnormal consciousness, craniocerebral CT should be done immediately and appropriate treatments should be applied. Craniotomy should be performed to clear the hematoma when needed.关键词
肝移植/手术后并发症/颅内出血Key words
liver transplantation/postoperative complications/intracranial hemorrhage分类
医药卫生引用本文复制引用
马毅,巫林伟,邰强,叶智明,孙灿辉,朱晓峰,何晓顺,王东平,王国栋,胡安斌,鞠卫强..原位肝移植术后颅内出血原因和处理[J].中国实用外科杂志,2011,31(8):703-704,2.基金项目
广东省科技计划项目(No:2008B030301296) （No:2008B030301296）
广东省自然科学基金(9151008901000052)资助 （9151008901000052）
