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女贞子化学成分研究

张廷芳 戴毅 屠凤娟 姚新生

中国药房2011,Vol.22Issue(31):2931-2933,3.
中国药房2011,Vol.22Issue(31):2931-2933,3.

女贞子化学成分研究

Chemical Constituents of Ligustrum lucidum

张廷芳 1戴毅 1屠凤娟 2姚新生3

作者信息

  • 1. 暨南大学中药及天然药物研究所,广州市510632
  • 2. 广东省中药药效物质基础及创新药物研究重点实验室,广州市510632
  • 3. 沈阳药科大学,沈阳市110016
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摘要

Abstract

OBJECTIVE: To study the chemical constituents of Ligustrum lucidum. METHODS: Isolation and purification were carried out by column chromatography over silica gel, RP-ODS, Sephadex LH-20 and RP-HPLC. The chemical constituents were identified by ESI-MS and NMR. RESULTS: Eight compounds were identified as oleanolic acid(l), 2α-hydroxy-oleanolic acid(2), 19α-hydroxy ursolic acid (3), tormentic acid (4),3β-O-(cis-p-Coumaroyl)-2α-hydroxy oleanolic acid (5), 3β-O-(trans-p-Coumaro-yl)-2α-hydroxy oleanolic acid (6), 3-O-cis-p-Coumaroyl tormentic acid (7), 3-0-trans-p-Coumaroyl tonnentic acid (8) .CONCLUSION: Compounds 3,5,7,8 are isolated from this genus for the first time.

关键词

女贞子/化学成分/结构鉴定

Key words

Ligustrum lucidum/Chemical constituents/Structure identification

分类

医药卫生

引用本文复制引用

张廷芳,戴毅,屠凤娟,姚新生..女贞子化学成分研究[J].中国药房,2011,22(31):2931-2933,3.

基金项目

深圳市基础研究计划项目(JC200903170506A) (JC200903170506A)

中国药房

OACSCDCSTPCD

1001-0408

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