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胃肠道及胃肠道外间质瘤216例临床病理学特点分析

沈旺 王新允 郑海燕 武力 袁海洪

中国实用外科杂志2011,Vol.31Issue(8):693-695,3.
中国实用外科杂志2011,Vol.31Issue(8):693-695,3.

胃肠道及胃肠道外间质瘤216例临床病理学特点分析

Clinicopathologic features of gastrointestinal stromal tumors and extragastrointestinal stromal tumors : an analysis of 216 cases

沈旺 1王新允 2郑海燕 3武力 2袁海洪2

作者信息

  • 1. 天津医科大学,天津300070
  • 2. 天津医科大学总医院,天津300052
  • 3. 天津医科大学第二医院,天津300211
  • 折叠

摘要

Abstract

Objective To investigate the features of clinicopathology and immunohistochemistry and the diagnostic criteria of gastrointestinal stromal tumor (CIST) and extragastrointestinal stromal tumor (EGIST). Methods The case data of 216 patients diagnosed as GIST and EGIST admitted between 2000 and 2009 in Tianjin Medical University General Hospital (17S patients) and the Second Hospital (41 patients) were analyzed retrospectively. Results In the 216 patients, 112 patients were male and 104 patients were female. The ratio of male to female was 1.077:1. The range in age was from IS to 91 years old. The median age was 58 years old. The tumors originated from the gastrointestinal tract were in 182 patients, and most of them were located in the stomach. The tumors originated from the extragastrointestinal tract were in 34 patients, and most of them were located in the mesenterium. The range in the diameter of tumors was from 0.8cm to 30.0cm. Tumors were composed of spindle cells and epithelioid cells. Cells arranged in interlacing, whorled and nesting. CD117-test was positive in 214 cases. Clinical manifestations were alimentary tract hemorrhage, abdominal pain, abdominal mass, intestinal obstruction and so on. Conclusion GISTs are more than EGISTs. Medium risk and high risk are predominant in the gastrointestinal tract, and high risk is predominant in the extragastrointestinal tract. Wide excision is the first choice in the clinical treatment principle.

关键词

胃肠道间质瘤/胃肠道外间质瘤/临床病理学特点

Key words

gastrointestinal stromal tumor/extragastrointestinal stromal tumor/clinicopathologic features

分类

医药卫生

引用本文复制引用

沈旺,王新允,郑海燕,武力,袁海洪..胃肠道及胃肠道外间质瘤216例临床病理学特点分析[J].中国实用外科杂志,2011,31(8):693-695,3.

中国实用外科杂志

OA北大核心CSCDCSTPCD

1005-2208

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