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脑功能区胶质瘤的现代手术策略

白红民 王伟民 梁树杰 李天栋 杨帅 王丽敏 何洹 施冲 王莎莎

临床神经外科杂志2011,Vol.8Issue(5):245-248,4.
临床神经外科杂志2011,Vol.8Issue(5):245-248,4.DOI:10.3969/j.issn.1672-7770.2011.05.007

脑功能区胶质瘤的现代手术策略

Modern surgical strategy for gliomas in eloquent areas

白红民 1王伟民 1梁树杰 2李天栋 1杨帅 1王丽敏 1何洹 3施冲 3王莎莎4

作者信息

  • 1. 510010,广州军区广州总医院神经外科
  • 2. 广州军区政治部东山干休所
  • 3. 510010,广州军区广州总医院麻醉科
  • 4. 510010,广州军区广州总医院超声影像科
  • 折叠

摘要

Abstract

Objective To study the new techniques and methods during surgery of brain gliomas located in supratentorial eloquent areas. Methods 112 patients with supratentorial gliomas were operated under awake anesthesia with ultrasonography for locating the tumor and intra-operative direct electrical stimulation ( DES) for functional mapping of the eloquent areas. The maximal resection of tumors and minimal damage of the eloquent areas were the surgical goal of all patients. All patients were followed up from 3 to 84 months. Results Of 112 patients, 107 were achieved awake and alert during brain mapping and resection of the lesions,99 were detected the motor areas by intra-operative direct electrical stimulation and 61 for language related cortex and 18 for sensory cortex. Of 112 patients,66 received totally resection of lesions,34 subtotal and 12 partial. 37 patients had transitory post-operative paralysis, 26 with transitory post-operative aphasia and 3 with permanent neurological sequelae. No patient died of surgery or complaint of pain recollection following operation. Conclusions Awake anesthesia, intra-operative DES and sonography are three core techniques for the resection of intrinsic cerebral tumors near the eloquent areas. This new concept allows an improvement in the quality of surgical resection of lesions on eloquent areas.

关键词

脑胶质瘤/脑功能区/直接电刺激/唤醒麻醉/超声

Key words

gliomas/ cerebral eloquent area/ direct electrical stimulation/ awake anesthesia/ sonography

分类

医药卫生

引用本文复制引用

白红民,王伟民,梁树杰,李天栋,杨帅,王丽敏,何洹,施冲,王莎莎..脑功能区胶质瘤的现代手术策略[J].临床神经外科杂志,2011,8(5):245-248,4.

临床神经外科杂志

OACSTPCD

1672-7770

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