临床神经外科杂志2011，Vol.8Issue(5)：234-236,3.DOI:10.3969/j.issn.1672-7770.2011.05.004
经蝶窦入路手术治疗垂体生长激素腺瘤
Transsphenoid surgery of pituitary adenoma of growth hormone
高广忠 1卞留贯2
作者信息
- 1. 225300,泰州市人民医院神经外科
- 2. 上海交通大学医学院附属瑞金医院神经外科
- 折叠
摘要
Abstract
Objective To explore the effect of tumor size, preoperative GH and the intraoperative growth hormone ( GH) measurement on the operative outcome in pituitary adenoma of GH. Methods The clinical data of 47 patients with acromegaly wereanalyzed retrospectively . The oral glucose tolerance test was used in pre-operative diagnosis and post-operative evaluation. All the patients were operated through transsphenoid and the intraoperative GH was measured in 19 patients. Results After the operation, the symptoms of acromegaly were significantly relieved in 30 patients. According to the criteria of remission, there were 29 (61. 7% ) . However, the remission rate of microadenoma (77. 7%) was significantly higher than that in macroadenoma (51. 7%). Conclusion The early diagnosis of acromegaly is the crucial of the improvement of surgical outcome. For the doubt cases,OGTT is helpful for the early diagnosis. The transsphenoid approach is the first choice of the treatment of acromegaly. The intraoperative GH measurement is valuable for the early evaluation of surgical outcome. If the intraoperative GH can be rapidly and timely measured, it will be effective to increase the remission rate.关键词
肢端肥大症/垂体瘤/经鼻蝶入路手术Key words
acromegaly/ pituitary adenoma/ thranssphenoid surgery分类
医药卫生引用本文复制引用
高广忠,卞留贯..经蝶窦入路手术治疗垂体生长激素腺瘤[J].临床神经外科杂志,2011,8(5):234-236,3.
