中山大学学报（医学科学版）2011，Vol.32Issue(4)：543-546,4.
HBV/HCV合并感染e抗原阴性和阳性患者临床特征对比分析
Comparative Study on Clinical Characteristics of HBV/HCV Co-infection Patients with HBeAg-positive and HBeAg-negative
摘要
Abstract
[Objective] The purpose of this study was to investigate the clinical characteristics in HBV/HCV co-infected patients with HBeAg-positive and HBeAg-negative. [Methods] A total of 186 HBV/HCV co-infected patients were retrospectively analyzed. The epidemiological, biochemical, and virological characteristics were collected. Univariate analysis was performed with the SPSS 16.0. [Results] Of the 186 cases, 140 were HBeAg-negative and 46 were HBeAg-positive. Compared with HBeAg-positive patients, HBeAg-negative patients had elder age, higher Tbil levels, higher virus levels and more blood transfusioner (P<0.05). However, ALT levels of HBeAg positive patients were higher than that of HBeAg negative patients (P = 0.031). The rate of HBV DNA positive in HBeAg negative patients was higher than that in HBeAg positive patients (P = 0.000). There was no difference of HCV RNA levels between HBeAg-positive patients and HBeAg-negative patients (P= 0.169). Other clinical characteristics was no difference (P> 0.05). [Conclusions] The clinical characteristics of HBV/HCV co-infection patients with HBeAg-positive and HBeAg-negative were different; these differences were also not same as that of HBV infected patients. HBeAg reflect the HBV DNA levels of HBV/HCV co-infected patients. HBeAg states has nothing to do with the level of HCV RNA.关键词
肝炎病毒，乙型；肝炎病毒，丙型；肝炎e抗原；合并感染Key words
hepatitis B virus/hepatitis C virus/hepatitis B e antigens/coinfection分类
医药卫生引用本文复制引用
张卡,曹红,洪晓绿,梁嘉仪,陈禄彪,舒欣,李刚,徐启桓..HBV/HCV合并感染e抗原阴性和阳性患者临床特征对比分析[J].中山大学学报（医学科学版）,2011,32(4):543-546,4.基金项目
广东省科技计划项目(2008B030301054；2008B030301052) （2008B030301054；2008B030301052）
