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药学干预对减少儿童抗生素相关性腹泻效果分析

郭永谊 卢倩文 郭毅

儿科药学杂志2011,Vol.17Issue(5):45-47,3.
儿科药学杂志2011,Vol.17Issue(5):45-47,3.

药学干预对减少儿童抗生素相关性腹泻效果分析

Analysis of Pharmaceutical Intervention Effect on Decreasing Antibiotic Associated Diarrhea in Children

郭永谊 1卢倩文 1郭毅1

作者信息

  • 1. 中山大学第五附属医院,广东珠海,519000
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摘要

Abstract

Objective; To investigate the influence of pharmaceutical intervention on decreasing the number of antibiotic associated diarrhea (AAD) in children. Methods; Cases of children in our hospital's pediatrics with respiratory infections were randomly selected from January 2008 to December 2009, for children with AAD-related factors Logistic regression analysis was performed, then the risk factors were selected for making appropriate pharmaceutical intervention measures. In 2010, cases were randomly selected every month and pharmaceutical intervention was taken for cases with AAD by Monitoring-Training-Plan (MTP) model. Results; Ages lower than 3 years and irrational use of antibiotics were risk factors of AAD. The application of probiotics was an independent protective factor of AAD. As a result of pharmaceutical intervention, the use of antibiotics tended to be rational, the incidence of AAD was significantly decreased from 39. 56% to 8.52% (P <0. 05 ). Conclusions; Effective pharmaceutical intervention could decrease the incidence of AAD and improve the quality of treatment.

关键词

药学干预/抗生素相关性腹泻/抗生素/危险因素/儿童

Key words

Pharmaceutical intervention/ Antibiotic associated diarrhea/ Antibiotics/ Risk factors/ Children

分类

医药卫生

引用本文复制引用

郭永谊,卢倩文,郭毅..药学干预对减少儿童抗生素相关性腹泻效果分析[J].儿科药学杂志,2011,17(5):45-47,3.

儿科药学杂志

OACSTPCD

1672-108X

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