军事医学2011，Vol.35Issue(9)：710-713,4.
拮抗细胞程序性坏死——机体应激损伤防护的新策略
Inhibition of cell programmed necrosis: a new strategy for stress damage protection
摘要
Abstract
Stress refers to the response of organisms, including humans and animals, to mental, emotional or physical stimulation. Excessive stress leads to stress damage by inducing tissue necrosis and organ exhaustion. Cell programmed necrosis is a new kind of programmed cell death with a precise target and signal transduction pathway, which plays a key role in regulating tissue damage induced by ischemic reperfusion, infection and inflammation. Furthermore, inhibition of programmed necrosis significantly prevents and cures stress damage in various animal models, so the proteins regulating programmed necrosis have become the new potent target for drug design in stress damage precaution and therapy.关键词
应激损伤/细胞程序性坏死/缺血再灌注损伤Key words
stress damage/cell programmed necrosis/ischemic reperfusion damage分类
生物科学引用本文复制引用
陈国柱,成祥,于晓妉..拮抗细胞程序性坏死——机体应激损伤防护的新策略[J].军事医学,2011,35(9):710-713,4.基金项目
国家科技重大专项"重大新药创制"资助项目(2009ZX09301-002) （2009ZX09301-002）
