中国药房2011，Vol.22Issue(35)：3298-3300,3.
头风宁滴丸中菊花的精制工艺研究
Study on Refining Process of Chrysanthemum morifalium in Toufengning Dropping Pills
摘要
Abstract
OBJECTIVE: To optimize macroporous adsorptive resins to purify Chtysanthemun morifalium in Toufengning dropping pills. METHODS: The type of macroporous resin, the maximum amount of physic liquor, the concentration of physic liquor and the concentration of elution solvent were optimized with the adsorption quantity and elution rate of chlorogenic acid as indexes with HPLC. RESULTS: The optimal conditions were as follows: the concentration of the pretreated physic liquor (chrysanthemum) was 0.075 g·mL-1, the maximum amount of physic liquor (C. Morifalium) was 1.2 g·mL-1 resin, which was sieved through HPD600 macroporous resin column, washed with water until appearing of colorless effluent, followed by elution with 70% ethanol (at a volume of 4-fold that of resin). CONCLUSION: The optimized technology is effective for purifying and enriching the chlorogenic acid, which achieve the purpose of purification.关键词
头风宁滴丸/菊花/绿原酸/大孔吸附树脂Key words
Toufengning dropping pills/Chrysanthemuy/Chlorogenic acid/Macroporous adsorption resin分类
医药卫生引用本文复制引用
朱怡洁,何伟,伍振峰..头风宁滴丸中菊花的精制工艺研究[J].中国药房,2011,22(35):3298-3300,3.基金项目
广东省科技计划项目(2009B040704004) （2009B040704004）
