临床神经外科杂志2011，Vol.8Issue(4)：192-194,3.DOI:10.3969/j.issn.1672-7770.2011.04.009
脑磁图对病灶性新皮质癫(疒间)术前评估的价值
Interictal magnetoencephalographic findings related with surgical outcomes in lesional neocortical epilepsy
摘要
Abstract
Objective To investigate whether interictal magnetoencephalography ( MEG) concordant with MRI findings could predict surgical outcome in patients with lesional refractory neocortical epilepsy( NE) . Methods 23 patients with lesional NE were studied. MEG was recorded for all patients and Synthetic aperture magnetometry ( SAM) with excess kurtosis ( g2) and conventional Equivalent Current Dipole (ECD) were used for MEG data analysis. 7 patients had a long-term extraoperative intracranial video electroencephalography ( iVEEG) monitoring. Surgical outcomes were assessed based on over one-year follow-up after surgery using Engel classification system. Results Both favorable outcomes (Engel class Ⅰ or Ⅱ ) and seizure freedom outcomes (Engel class IA) were higher for the concordance condition ( MEG findings are concordant with MRI) versus the discordance condition. Conclusions This study demonstrates that a favorable postsurgical outcome can be obtained in most patients with concordant MEG and MRI results even without extraoperative ivEEG monitoring, extraoperative iVEEG monitoring seems to be unnecessary to those patients ,but it remains prerequisite to the patients with discordant MEG and MRI findings or to those needing eloquent areas mapping.关键词
脑磁图/癫(疒间)手术/新皮质癫(疒间)/病灶性Key words
magnetoencephalography/ epilepsy surgery / neocortical epilepsy/ lesional分类
医药卫生引用本文复制引用
张锐,刘宏毅,邹元杰,杨坤,吴婷,刘文,傅震..脑磁图对病灶性新皮质癫(疒间)术前评估的价值[J].临床神经外科杂志,2011,8(4):192-194,3.基金项目
南京市市医药卫生科研课题(NO.YKK08038) （NO.YKK08038）
南京市科学技术局资助项目(NO.2009sc334005) （NO.2009sc334005）
