分析化学2011,Vol.39Issue(7):953-962,10.DOI:10.3724/SP.J.1096.2011.00953
脱氧核糖核酸分子设计在电化学生物传感器中的应用
Deoxyribonucleic Acid Molecular Design for Electrochemical Biosensors
摘要
Abstract
A new electrochemical biosensors based on the DNA configuration switch was represented in this review. Special DNA probes (stem-loop or aptamers etc. ) on the electrode surface dramatically change their configuration on the combination of target molecular giving birth to a detectable electro chemical signal. This strategy attracts extensive research interesting for its easier operation and less unspecific absorption, To this day, its analysis performance has been markedly developed with an expanding application. Here, we summarize the history of these sensors.关键词
电化学传感器/基因传感器/核酸适配体/分子信标/评述Key words
Eletrochemical biosensor/ Deoxyribonucleic acid biosensor/ Aptamer/ Molecular beacon/Review引用本文复制引用
刘刚,万莹,邹子英,任淑贞,樊春海..脱氧核糖核酸分子设计在电化学生物传感器中的应用[J].分析化学,2011,39(7):953-962,10.基金项目
本文系国家自然科学基金(No.20725516)、国家质检总局科技计划项目(No.HOORJ906)和上海市科委科研计划项目(No.10142201700)资助 (No.20725516)