分析化学2011，Vol.39Issue(7)：1015-1020,6.DOI:10.3724/SP.J.1096.2011.01015
葡萄糖检测用分子印迹光子晶体的研究
Molecularly Imprinted Photonic Crystal for Detection of Glucose
摘要
Abstract
A three-dimensionally ordered, macroporous, inverse-opal glucose molecularly imprinted polymer crystal (MIPC) film was synthesized by the inverted colloidal-crystal template technique.Preparation of our MIPC was carried out by thermo-poymerization of monomers (2-hydroxyethyl methacrylate and Ni-sopropylacrylamide) , covalent recognizer (4-ethylenyl phenylboronic acid) , and cross-linker (N, N'-Methylenebisacrylamide) with poly ( methyl-methacrylate) ( PMMA) particle array as template , followed by chemical removal of the template using acetone. Due to its 3D-ordered macroporous arrays with molecular imprinting, nanocavities, the formed photonic hydrogel allows rapid and selective detection of the target glucose. The glucose adsorption amount of our MIP was 3. 2 mg/g in 3 min which is two times more than that of other analogues. The diffraction wavelength of the MIPC redshifts was more than 150 nm in response to 0. 02 mol/L of glucose. Our results revealed that MIPC could provide a novel non-invasive approach for glucose detection in tears or urine and exhibit a promising potential for development of new glucose monitoring technology.关键词
光子晶体/分子印迹/葡萄糖检测/自组装Key words
Photonic crystals / molecular imprinting / Glucose detection/ Self-assembly引用本文复制引用
薛飞,孟子晖,段廷蕊,薛敏,刘烽,王一飞,韦泽全,王淼,张盼,袁梓高..葡萄糖检测用分子印迹光子晶体的研究[J].分析化学,2011,39(7):1015-1020,6.基金项目
本文系国家自然科学基金(No.20775007),863计划(No.2007AA1OZ433)和环境毒理国家重点实验室开放基金(No.KF2009-08)资助 （No.20775007）
