广西医学2011,Vol.33Issue(11):1403-1405,3.
急性心肌梗死冠脉支架植入前后血液T细胞亚群水平改变的观察
Observation on Serum Changes of T Cell Subsets before and after Coronary Stent Implantation in Acute Myocardial Infarction
摘要
Abstract
To investigate the serum level of T-lymphocyte subpopulations CD3, CD4, CD8 before and after coronary stent implantation in acute myocardial infarction( AMI ). Methods The serum levels of T-lymphocyte subpopulations in from 57 patients with AMI before/after coronary stent implantation, and 60 normal controls( control group )were assayed by SAP method. Results The level of CD3 + , CD4 + and the ratio of CD4 +/CD8 + in both the group before implantation and after implantation in first day were less than those in seventh day and control group, but the CD8 + was highe rthan those in seventh day and control group( P < 0.05 ). Conclusion The changes in cellular immunity function in AMI patients may affect the pathogenesis of AMI. T-lymphocyte subsets can estimate the severity of AMI, and to assess the extent of the disease improved after coronary stent implantation, also provides a new direction for the future treatment of immune intervention in AMI.关键词
急性心肌梗死/冠脉支架植入/免疫/T淋巴细胞亚群Key words
Acute myocardial infarction/Coronary stent implantation/Immunity/T-lymphocyte subpopulations分类
医药卫生引用本文复制引用
唐剑,黄达军,蓝峰,郑赓唐,陈昶..急性心肌梗死冠脉支架植入前后血液T细胞亚群水平改变的观察[J].广西医学,2011,33(11):1403-1405,3.基金项目
广西医药卫生科学研究基金资助项目(Z2009352) (Z2009352)