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急性心肌梗死冠脉支架植入前后血液T细胞亚群水平改变的观察

唐剑 黄达军 蓝峰 郑赓唐 陈昶

广西医学2011,Vol.33Issue(11):1403-1405,3.
广西医学2011,Vol.33Issue(11):1403-1405,3.

急性心肌梗死冠脉支架植入前后血液T细胞亚群水平改变的观察

Observation on Serum Changes of T Cell Subsets before and after Coronary Stent Implantation in Acute Myocardial Infarction

唐剑 1黄达军 1蓝峰 1郑赓唐 1陈昶1

作者信息

  • 1. 广西医科大学第七附属医院暨梧州市工人医院,梧州市,543001
  • 折叠

摘要

Abstract

To investigate the serum level of T-lymphocyte subpopulations CD3, CD4, CD8 before and after coronary stent implantation in acute myocardial infarction( AMI ). Methods The serum levels of T-lymphocyte subpopulations in from 57 patients with AMI before/after coronary stent implantation, and 60 normal controls( control group )were assayed by SAP method. Results The level of CD3 + , CD4 + and the ratio of CD4 +/CD8 + in both the group before implantation and after implantation in first day were less than those in seventh day and control group, but the CD8 + was highe rthan those in seventh day and control group( P < 0.05 ). Conclusion The changes in cellular immunity function in AMI patients may affect the pathogenesis of AMI. T-lymphocyte subsets can estimate the severity of AMI, and to assess the extent of the disease improved after coronary stent implantation, also provides a new direction for the future treatment of immune intervention in AMI.

关键词

急性心肌梗死/冠脉支架植入/免疫/T淋巴细胞亚群

Key words

Acute myocardial infarction/Coronary stent implantation/Immunity/T-lymphocyte subpopulations

分类

医药卫生

引用本文复制引用

唐剑,黄达军,蓝峰,郑赓唐,陈昶..急性心肌梗死冠脉支架植入前后血液T细胞亚群水平改变的观察[J].广西医学,2011,33(11):1403-1405,3.

基金项目

广西医药卫生科学研究基金资助项目(Z2009352) (Z2009352)

广西医学

OACSTPCD

0253-4304

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